Mephisto's Brain

Mephisto's Brain
  • Mephisto's Brain

Uber Izual drops Mephisto's Brain in Furnace of Pain, in Hell only. Transmute one of each organ in the Horadric CubeHoradric Cube in Harrogath to open Uber Tristram, the finale of The Pandemonium EventQuestCompleteThe Pandemonium Event:

Horadric Cube Recipes using a Mephisto's Brain

Portal to Tristram (Pandemonium Finale)

Diablo's HornBaal's EyeMephisto's Brain
horadric cube interface

Other event items

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